Onset and spread of dyskinesias and motor symptoms in Parkinson's disease
Identifieur interne : 000A11 ( Main/Exploration ); précédent : 000A10; suivant : 000A12Onset and spread of dyskinesias and motor symptoms in Parkinson's disease
Auteurs : Giovanni Fabbrini [Italie] ; Giovanni Defazio [Italie] ; Carlo Colosimo [Italie] ; Antonio Suppa [Italie] ; Maria Bloise [Italie] ; Alfredo Berardelli [Italie]Source :
- Movement Disorders [ 0885-3185 ] ; 2009-10-30.
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Abstract
We retrospectively investigated in consecutive Parkinson's disease (PD) outpatients the relationship between the body region in which LID first appeared and the body region where Parkinsonian motor symptoms started. We also studied the spread of LID and motor symptoms to other body parts during the progression of PD. Of the 307 PD patients investigated, 99 with LID were enrolled in the study. In these 99 patients, LID started unilaterally in the limbs in 44, bilaterally in the limbs in 26, and in craniocervical region in 29, whereas motor symptoms invariably started in the limbs. LID and motor symptoms started in the same body region in less than half of the patients studied. Of the 99 patients studied, 69 had LID spread to at least another body region during the course of their disease. In this group, clinical examination yielded a significantly different distribution of LID and motor symptoms. These findings suggest that the onset and spread of LID and motor symptoms may follow different anatomical patterns. © 2009 Movement Disorder Society
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DOI: 10.1002/mds.22703
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Disord.</title><idno type="ISSN">0885-3185</idno><idno type="eISSN">1531-8257</idno><imprint><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><pubPlace>Hoboken</pubPlace><date type="published" when="2009-10-30">2009-10-30</date><biblScope unit="volume">24</biblScope><biblScope unit="issue">14</biblScope><biblScope unit="page" from="2091">2091</biblScope><biblScope unit="page" to="2096">2096</biblScope></imprint><idno type="ISSN">0885-3185</idno></series><idno type="istex">BB4F3066149608A09947959E0C27693D79F5B9B4</idno><idno type="DOI">10.1002/mds.22703</idno><idno type="ArticleID">MDS22703</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0885-3185</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>L‐dopa</term><term>Parkinson disease</term><term>basal ganglia</term><term>dyskinesias</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">We retrospectively investigated in consecutive Parkinson's disease (PD) outpatients the relationship between the body region in which LID first appeared and the body region where Parkinsonian motor symptoms started. We also studied the spread of LID and motor symptoms to other body parts during the progression of PD. Of the 307 PD patients investigated, 99 with LID were enrolled in the study. In these 99 patients, LID started unilaterally in the limbs in 44, bilaterally in the limbs in 26, and in craniocervical region in 29, whereas motor symptoms invariably started in the limbs. LID and motor symptoms started in the same body region in less than half of the patients studied. Of the 99 patients studied, 69 had LID spread to at least another body region during the course of their disease. In this group, clinical examination yielded a significantly different distribution of LID and motor symptoms. These findings suggest that the onset and spread of LID and motor symptoms may follow different anatomical patterns. © 2009 Movement Disorder Society</div></front></TEI><affiliations><list><country><li>Italie</li></country><region><li>Latium</li></region><settlement><li>Rome</li></settlement></list><tree><country name="Italie"><region name="Latium"><name sortKey="Fabbrini, Giovanni" sort="Fabbrini, Giovanni" uniqKey="Fabbrini G" first="Giovanni" last="Fabbrini">Giovanni Fabbrini</name></region><name sortKey="Berardelli, Alfredo" sort="Berardelli, Alfredo" uniqKey="Berardelli A" first="Alfredo" last="Berardelli">Alfredo Berardelli</name><name sortKey="Bloise, Maria" sort="Bloise, Maria" uniqKey="Bloise M" first="Maria" last="Bloise">Maria Bloise</name><name sortKey="Colosimo, Carlo" sort="Colosimo, Carlo" uniqKey="Colosimo C" first="Carlo" last="Colosimo">Carlo Colosimo</name><name sortKey="Defazio, Giovanni" sort="Defazio, Giovanni" uniqKey="Defazio G" first="Giovanni" last="Defazio">Giovanni Defazio</name><name sortKey="Suppa, Antonio" sort="Suppa, Antonio" uniqKey="Suppa A" first="Antonio" last="Suppa">Antonio Suppa</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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